diff --git a/esphome/components/tinyusb/__init__.py b/esphome/components/tinyusb/__init__.py
index 53c4ab00734..7ad88d3018d 100644
--- a/esphome/components/tinyusb/__init__.py
+++ b/esphome/components/tinyusb/__init__.py
@@ -1,4 +1,4 @@
-from esphome import final_validate as fv
+from esphome import automation, final_validate as fv, pins
 import esphome.codegen as cg
 from esphome.components import esp32
 from esphome.components.esp32 import (
@@ -12,17 +12,22 @@ from esphome.components.esp32 import (
 )
 import esphome.config_validation as cv
 from esphome.const import CONF_HARDWARE_UART, CONF_ID
+from esphome.core import ID
+from esphome.cpp_generator import MockObj, TemplateArgsType
 from esphome.types import ConfigType
 
 CODEOWNERS = ["@kbx81"]
 CONFLICTS_WITH = ["usb_host"]
 
+CONF_ON_MOUNT = "on_mount"
+CONF_ON_UNMOUNT = "on_unmount"
 CONF_USB_LANG_ID = "usb_lang_id"
 CONF_USB_MANUFACTURER_STR = "usb_manufacturer_str"
 CONF_USB_PRODUCT_ID = "usb_product_id"
 CONF_USB_PRODUCT_STR = "usb_product_str"
 CONF_USB_SERIAL_STR = "usb_serial_str"
 CONF_USB_VENDOR_ID = "usb_vendor_id"
+CONF_VBUS_MONITOR_PIN = "vbus_monitor_pin"
 
 # Components that provide a USB device class (CDC, HID, MSC, ...) on top of
 # tinyusb. Configuring `tinyusb:` without any of these triggers a 5s hang in
@@ -33,6 +38,20 @@ _USB_CLASS_COMPONENTS = ("usb_cdc_acm",)
 
 tinyusb_ns = cg.esphome_ns.namespace("tinyusb")
 TinyUSB = tinyusb_ns.class_("TinyUSB", cg.Component)
+IsMountedCondition = tinyusb_ns.class_("IsMountedCondition", automation.Condition)
+
+_CALLBACK_AUTOMATIONS = (
+    automation.CallbackAutomation(
+        CONF_ON_MOUNT,
+        "add_on_mount_state_callback",
+        forwarder=automation.TriggerOnTrueForwarder,
+    ),
+    automation.CallbackAutomation(
+        CONF_ON_UNMOUNT,
+        "add_on_mount_state_callback",
+        forwarder=automation.TriggerOnFalseForwarder,
+    ),
+)
 
 CONFIG_SCHEMA = cv.All(
     cv.Schema(
@@ -44,6 +63,18 @@ CONFIG_SCHEMA = cv.All(
             cv.Optional(CONF_USB_MANUFACTURER_STR, default="ESPHome"): cv.string,
             cv.Optional(CONF_USB_PRODUCT_STR, default="ESPHome"): cv.string,
             cv.Optional(CONF_USB_SERIAL_STR, default=""): cv.string,
+            # esp_tinyusb monitors VBUS on the S31 through a GPIO interrupt and needs
+            # the GPIO ISR service installed first, which would collide with the esp32
+            # platform's own lazy install and disable other interrupts. The other
+            # variants watch the pin in the OTG hardware.
+            cv.Optional(CONF_VBUS_MONITOR_PIN): cv.All(
+                pins.internal_gpio_input_pin_number,
+                esp32.only_on_variant(
+                    unsupported=[VARIANT_ESP32S31], msg_prefix=CONF_VBUS_MONITOR_PIN
+                ),
+            ),
+            cv.Optional(CONF_ON_MOUNT): automation.validate_automation({}),
+            cv.Optional(CONF_ON_UNMOUNT): automation.validate_automation({}),
         }
     ).extend(cv.COMPONENT_SCHEMA),
     esp32.only_on_variant(
@@ -93,9 +124,28 @@ async def to_code(config: ConfigType) -> None:
     cg.add(var.set_usb_desc_product(config[CONF_USB_PRODUCT_STR]))
     if config[CONF_USB_SERIAL_STR]:
         cg.add(var.set_usb_desc_serial(config[CONF_USB_SERIAL_STR]))
+    if (vbus_pin := config.get(CONF_VBUS_MONITOR_PIN)) is not None:
+        cg.add(var.set_vbus_monitor_pin(vbus_pin))
+
+    await automation.build_callback_automations(var, config, _CALLBACK_AUTOMATIONS)
 
     add_idf_component(name="espressif/esp_tinyusb", ref="2.2.1")
 
     add_idf_sdkconfig_option("CONFIG_TINYUSB_DESC_USE_ESPRESSIF_VID", False)
     add_idf_sdkconfig_option("CONFIG_TINYUSB_DESC_USE_DEFAULT_PID", False)
     add_idf_sdkconfig_option("CONFIG_TINYUSB_DESC_BCD_DEVICE", 0x0100)
+
+
+@automation.register_condition(
+    "tinyusb.is_mounted",
+    IsMountedCondition,
+    cv.Schema({cv.GenerateID(): cv.use_id(TinyUSB)}),
+)
+async def tinyusb_is_mounted_to_code(
+    config: ConfigType,
+    condition_id: ID,
+    template_arg: cg.TemplateArguments,
+    args: TemplateArgsType,
+) -> MockObj:
+    paren = await cg.get_variable(config[CONF_ID])
+    return cg.new_Pvariable(condition_id, template_arg, paren)
diff --git a/esphome/components/tinyusb/tinyusb_component.cpp b/esphome/components/tinyusb/tinyusb_component.cpp
index c8c36f0ffb6..3fab9de0086 100644
--- a/esphome/components/tinyusb/tinyusb_component.cpp
+++ b/esphome/components/tinyusb/tinyusb_component.cpp
@@ -9,6 +9,14 @@ namespace esphome::tinyusb {
 
 static const char *const TAG = "tinyusb";
 
+// Runs on the TinyUSB task: only wake the main loop, which reads the state and runs
+// the automations.
+static void tinyusb_event_cb(tinyusb_event_t *event, void *arg) {
+  if (event->id == TINYUSB_EVENT_ATTACHED || event->id == TINYUSB_EVENT_DETACHED) {
+    static_cast<TinyUSB *>(arg)->enable_loop_soon_any_context();
+  }
+}
+
 void TinyUSB::setup() {
   // Use the device's MAC address as its serial number if no serial number is defined
   if (this->string_descriptor_[SERIAL_NUMBER] == nullptr) {
@@ -21,6 +29,12 @@ void TinyUSB::setup() {
   this->tusb_cfg_ = TINYUSB_DEFAULT_CONFIG();
   this->tusb_cfg_.port = TINYUSB_PORT_FULL_SPEED_0;
   this->tusb_cfg_.phy.skip_setup = false;
+  // Without VBUS monitoring the OTG core only sees a cable pull as the bus going idle
+  // (a suspend), so TinyUSB never reports a detach and stays "mounted".
+  if (this->vbus_monitor_pin_ >= 0) {
+    this->tusb_cfg_.phy.self_powered = true;
+    this->tusb_cfg_.phy.vbus_monitor_io = this->vbus_monitor_pin_;
+  }
   this->tusb_cfg_.descriptor = {
       .device = &this->usb_descriptor_,
       .string = this->string_descriptor_,
@@ -42,11 +56,26 @@ void TinyUSB::setup() {
   }
 #endif
 
+  this->tusb_cfg_.event_cb = tinyusb_event_cb;
+  this->tusb_cfg_.event_arg = this;
   esp_err_t result = tinyusb_driver_install(&this->tusb_cfg_);
   if (result != ESP_OK) {
     ESP_LOGE(TAG, "tinyusb_driver_install failed: %s", esp_err_to_name(result));
     this->mark_failed();
+    return;
   }
+  // loop() only reports mount changes; the mount hooks wake it when one happens.
+  this->disable_loop();
+}
+
+void TinyUSB::loop() {
+  const bool mounted = tud_mounted();
+  if (mounted != this->last_reported_mounted_) {
+    this->last_reported_mounted_ = mounted;
+    ESP_LOGD(TAG, "USB host %s", mounted ? LOG_STR_LITERAL("mounted") : LOG_STR_LITERAL("unmounted"));
+    this->mount_state_callback_.call(mounted);
+  }
+  this->disable_loop();
 }
 
 void TinyUSB::dump_config() {
@@ -56,9 +85,12 @@ void TinyUSB::dump_config() {
                 "  Vendor ID: 0x%04X\n"
                 "  Manufacturer: '%s'\n"
                 "  Product: '%s'\n"
-                "  Serial: '%s'\n",
+                "  Serial: '%s'",
                 this->usb_descriptor_.idProduct, this->usb_descriptor_.idVendor, this->string_descriptor_[MANUFACTURER],
                 this->string_descriptor_[PRODUCT], this->string_descriptor_[SERIAL_NUMBER]);
+  if (this->vbus_monitor_pin_ >= 0) {
+    ESP_LOGCONFIG(TAG, "  VBUS Monitor Pin: GPIO%d", this->vbus_monitor_pin_);
+  }
 }
 
 }  // namespace esphome::tinyusb
diff --git a/esphome/components/tinyusb/tinyusb_component.h b/esphome/components/tinyusb/tinyusb_component.h
index e85fea9d21a..f7f574ec6d5 100644
--- a/esphome/components/tinyusb/tinyusb_component.h
+++ b/esphome/components/tinyusb/tinyusb_component.h
@@ -1,8 +1,11 @@
 #pragma once
 #if defined(USE_ESP32_VARIANT_ESP32P4) || defined(USE_ESP32_VARIANT_ESP32S2) || defined(USE_ESP32_VARIANT_ESP32S3) || \
     defined(USE_ESP32_VARIANT_ESP32S31) || defined(USE_ESP32_VARIANT_ESP32H4)
+#include "esphome/core/automation.h"
 #include "esphome/core/component.h"
+#include "esphome/core/helpers.h"
 
+#include <utility>
 #include "tinyusb.h"
 #include "tusb.h"
 
@@ -23,9 +26,17 @@ static const char *const DEFAULT_USB_STR = "ESPHome";
 class TinyUSB final : public Component {
  public:
   void setup() override;
+  void loop() override;
   void dump_config() override;
   float get_setup_priority() const override { return setup_priority::BUS; }
 
+  /// True while a USB host has enumerated and configured the device.
+  bool is_mounted() const { return tud_mounted(); }
+  /// Called with the new mount state whenever a host mounts or unmounts the device.
+  template<typename F> void add_on_mount_state_callback(F &&callback) {
+    this->mount_state_callback_.add(std::forward<F>(callback));
+  }
+
   void set_usb_desc_product_id(uint16_t product_id) { this->usb_descriptor_.idProduct = product_id; }
   void set_usb_desc_vendor_id(uint16_t vendor_id) { this->usb_descriptor_.idVendor = vendor_id; }
   void set_usb_desc_lang_id(uint16_t lang_id) {
@@ -37,6 +48,8 @@ class TinyUSB final : public Component {
   }
   void set_usb_desc_product(const char *usb_desc_product) { this->string_descriptor_[PRODUCT] = usb_desc_product; }
   void set_usb_desc_serial(const char *usb_desc_serial) { this->string_descriptor_[SERIAL_NUMBER] = usb_desc_serial; }
+  /// Self-powered device: watch VBUS on this GPIO so a cable pull becomes a detach.
+  void set_vbus_monitor_pin(int pin) { this->vbus_monitor_pin_ = static_cast<int8_t>(pin); }
 
  protected:
   char usb_desc_lang_id_[2] = {0x09, 0x04};  // defaults to english
@@ -50,6 +63,11 @@ class TinyUSB final : public Component {
       nullptr,                  // 5: Terminator
   };
 
+  LazyCallbackManager<void(bool)> mount_state_callback_;
+  // Edge-detection baseline for loop(); is_mounted() reads the live state instead.
+  bool last_reported_mounted_{false};
+  int8_t vbus_monitor_pin_{-1};
+
   tinyusb_config_t tusb_cfg_{};
   tusb_desc_device_t usb_descriptor_{
       .bLength = sizeof(tusb_desc_device_t),
@@ -69,6 +87,15 @@ class TinyUSB final : public Component {
   };
 };
 
+template<typename... Ts> class IsMountedCondition final : public Condition<Ts...> {
+ public:
+  explicit IsMountedCondition(TinyUSB *parent) : parent_(parent) {}
+  bool check(const Ts &...) override { return this->parent_->is_mounted(); }
+
+ protected:
+  TinyUSB *parent_;
+};
+
 }  // namespace esphome::tinyusb
 #endif  // USE_ESP32_VARIANT_ESP32P4 || USE_ESP32_VARIANT_ESP32S2 || USE_ESP32_VARIANT_ESP32S3 ||
         // USE_ESP32_VARIANT_ESP32S31 || USE_ESP32_VARIANT_ESP32H4
diff --git a/tests/components/tinyusb/common.yaml b/tests/components/tinyusb/common.yaml
index 674e89dbe87..32db1999afe 100644
--- a/tests/components/tinyusb/common.yaml
+++ b/tests/components/tinyusb/common.yaml
@@ -6,6 +6,15 @@ tinyusb:
   usb_product_str: ESPHomeTestProduct
   usb_serial_str: ESPHomeTestSerialNumber
   usb_vendor_id: 0x2345
+  on_mount:
+    - logger.log: USB host mounted
+    - if:
+        condition:
+          tinyusb.is_mounted:
+        then:
+          - logger.log: USB host is mounted
+  on_unmount:
+    - logger.log: USB host unmounted
 
 # tinyusb requires at least one USB class companion; usb_cdc_acm satisfies that.
 usb_cdc_acm:
diff --git a/tests/components/tinyusb/test.esp32-p4-idf.yaml b/tests/components/tinyusb/test.esp32-p4-idf.yaml
index dade44d145b..7a37fcf41b8 100644
--- a/tests/components/tinyusb/test.esp32-p4-idf.yaml
+++ b/tests/components/tinyusb/test.esp32-p4-idf.yaml
@@ -1 +1,7 @@
-<<: !include common.yaml
+packages:
+  tinyusb: !include common.yaml
+
+# VBUS monitoring is per variant: the OTG hardware watches the pin here, while the
+# S31 would need the GPIO ISR path and rejects the key.
+tinyusb:
+  vbus_monitor_pin: 4
diff --git a/tests/components/tinyusb/test.esp32-s2-idf.yaml b/tests/components/tinyusb/test.esp32-s2-idf.yaml
index 09b98ada401..67ea24f2c6c 100644
--- a/tests/components/tinyusb/test.esp32-s2-idf.yaml
+++ b/tests/components/tinyusb/test.esp32-s2-idf.yaml
@@ -1,4 +1,10 @@
-<<: !include common.yaml
+packages:
+  tinyusb: !include common.yaml
+
+# VBUS monitoring is per variant: the OTG hardware watches the pin here, while the
+# S31 would need the GPIO ISR path and rejects the key.
+tinyusb:
+  vbus_monitor_pin: 4
 
 # S2 defaults logger to USB_CDC, which conflicts with tinyusb on the shared
 # USB OTG peripheral; route the logger to UART0 so the fixture builds.
diff --git a/tests/components/tinyusb/test.esp32-s3-idf.yaml b/tests/components/tinyusb/test.esp32-s3-idf.yaml
index dade44d145b..7a37fcf41b8 100644
--- a/tests/components/tinyusb/test.esp32-s3-idf.yaml
+++ b/tests/components/tinyusb/test.esp32-s3-idf.yaml
@@ -1 +1,7 @@
-<<: !include common.yaml
+packages:
+  tinyusb: !include common.yaml
+
+# VBUS monitoring is per variant: the OTG hardware watches the pin here, while the
+# S31 would need the GPIO ISR path and rejects the key.
+tinyusb:
+  vbus_monitor_pin: 4